Collagen and Skin Ageing: How to Boost Production for Skin Longevity

When it comes to visibly firm, smooth, youthful-looking skin, collagen is key. Often described as the building blocks of the skin, collagen is a structural protein that gives skin its strength, bounce and resilience. In fact, it’s the most abundant protein in the human body, found not just in the skin, but also in bones, ligaments and connective tissues.

Within the skin, collagen is produced by specialised cells called fibroblasts that live in the deepest layers of the skin. These hardworking cells help build a supportive skin matrix, think strong, twisting ‘ropes’ woven into a sturdy mesh. This scaffolding holds the skin firm, giving it a supple, lifted appearance.

Collagen Decline: What Happens as We Age?

Here’s the catch: collagen doesn’t last forever. As we age, our bodies naturally produce less collagen from our mid-20s and external aggressors like UV rays and pollution accelerate its breakdown^[1]. An easy way to visualise this decline is to think of the collagen in your skin as the wooden slats of a bed frame holding up a mattress. When the slats are new and strong, the mattress remains firm and supported, but over time, these slats can weaken or break, causing the mattress to lose its support and sag. The same goes for your skin; with collagen depletion comes visible signs of ageing such as wrinkles, sagging and dullness.

So, Does Topical Collagen Work?

The secret to combating the visible signs of skin ageing is replenishing the collagen your skin loses over time, but like with many things in the human body, it’s not (quite) that simple.

With so many products on the market promising ‘collagen-rich’ results, you might be wondering:, why not just apply collagen directly to the skin? The answer lies in the science, and collagen molecules are simply too large to penetrate the skin barrier. This means that topical collagen can sit on the surface and hydrate temporarily, but it can’t reach the deeper layers where real structural change happens.

That’s why, at Medik8, we focus on advanced formulas that help stimulate your skin’s own collagen production from within.

Inside The Lab

We put our latest innovation to the test in a controlled laboratory setting with an independent placebo-controlled ex vivo study. We chose an ex vivo collagen study to measure results beneath the surface, using real human skin tissue in lab conditions.

We measured the levels of type 1 collagen (the most abundant collagen in the skin) after 24 hours and 72 hours with Advanced Pro-Collagen+ Peptide Cream.

This advanced testing method allowed us to prove a 45% increase in collagen production, which standard user trials can’t capture^[2]. It’s all part of our commitment to science-backed skincare that delivers visible, lasting results.

The Results:
Proven Collagen Skincare That Delivers

We know you’ve heard it all before: ‘topical collagen doesn’t work.’ That’s why our latest innovation isn’t about adding collagen. It’s about activating what’s already yours, backed by science, proven in the lab and loved in real life.

Advanced Pro-Collagen+ Peptide Cream is expertly formulated with cutting-edge ingredients that work in perfect synergy to stimulate collagen production, restore skin structure, and support long-term skin longevity. This is clinically proven collagen power.

^{References
[1] Varani, J., Dame, M. K., Rittie, L., Fligiel, S. E., Kang, S., Fisher, G. J., & Voorhees, J. J. (2006). Decreased collagen production in chronologically aged skin: roles of age-dependent alteration in fibroblast function and defective mechanical stimulation. The American journal of pathology, 168(6), 1861–1868.
[2] Proven via ex vivo collagen study using Advanced Pro-Collagen+ Peptide Cream
[3] Proven via independent clinical study on Advanced Pro-Collagen+ Peptide Cream on 60 volunteers over 1 week}