Skincare with Peptides

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Peptides are essential building blocks of proteins that keep the skin looking smooth, firm, and youthful. Applied topically, they can help to stimulate collagen and boost elasticity, visibly reducing the appearance of fine lines and wrinkles. Our innovative peptide skincare products feature expertly engineered peptide combinations for visible brightening, clarifying, and hydrating effects, delivering maximum results.
Liquid Peptides Advanced MP
Liquid Peptides Advanced MP
Morning
Evening
Deep set lines & wrinkles
Liquid Peptides Advanced MP Wrinkle reduction serum with 30% multi-peptide complex - proven to deliver results in as little as 10 minutes.¹
Full Size (30ml) | £82
An open jar of Medik8 Advanced Pro-Collagen+ Peptide Cream displaying a swirl of white cream on a clean white background. Text on the jar describes it as a "Rejuvenating Anti-Wrinkle Moisturiser with GF MiniProtein & NAD+ Boost". A graphic in the top left corner highlights "GF MINIPROTEINS™ & NAD+ LONGEVITY BOOSTER".
Black backdrop with the Advanced Pro-Collagen+ Peptide Cream jar and text reading: 'Helps to increase collagen production by 45%*.' Benefit claims include firmer skin, reduced wrinkles, and increased elasticity. Asterisk notes this is from an ex vivo study.
Morning
Evening
Fine lines & wrinkles
Advanced Pro-Collagen+ Peptide Cream Rejuvenating Anti-Wrinkle Moisturiser With GF MiniProteinTM & NAD+ Longevity Booster
Full size (50ml) | £82
Festive Kit
Firm Favourites
A Liquid Peptides Advanced MP black pump bottle and an Exo-PDRN Prismatic+ white pump bottle wrapped in a purple ribbon against a deep burgundy background. Text highlights that Liquid Peptides Advanced MP "delivers advanced deep-set wrinkle reduction," and Exo-PDRN Prismatic+ "supports visibly enhanced skin luminosity & resilience."
Morning
Evening
Firm Favourites Lifting & Rejuvenating Duo
£112
Festive Kit
Medik8 Age-Defying Essentials gift set featuring skincare products including Crystal Retinal, Advanced Pro-Collagen+ Peptide Cream, and Liquid Peptides Advanced MP Deluxe Sample, presented in a white box with blue ribbons on a dark blue background. A 'Saving £38' promotional badge is visible in the top left.
Three Medik8 products wrapped in a blue ribbon against a dark blue background, with text highlighting key benefits for each. The Crystal Retinal 6 tube "Visibly firms, brightens & smooths the skin," the Liquid Peptides Advanced MP deluxe sample "Delivers advanced deep-set wrinkle reduction," and the Advanced Pro-Collagen+ Peptide Cream jar "Supports visible skin firmness & elasticity."
Age-Defying Essentials Ultimate Skin Renewing Heroes
£113
Medik8 Niacinamide Peptides serum bottle with a white pump top, resting on a white surface with a smear of white serum behind it.
A split image showing a close-up of skin texture labelled "Before" and "After 4 Weeks," highlighting improvements. Text on the left lists benefits: "Reduced blemishes," "Improved skin texture," "Reduced pore size," and "Soothed visible redness."
Morning
Evening
Enlarged pores & blemishes
Niacinamide Peptides 10% Niacinamide Serum with Peptides & NAG
Full size (30ml) | £49
An open frosted glass jar of Medik8 Total Moisture Daily Facial Cream with a peak of white cream on top, set against a clean white background. Badges in the top corners indicate it is a "Daisy Beauty Awards Vinnare 2025" (Winner) and "Dermatologist Recommended."
An image split between a white cream texture background and a smiling woman touching her radiant face. Text highlights key benefits with checkmarks: "Infuses moisture into the lowest layers of your skin," "Instantly plumps and softens your skin," and "Clinically proven to boost skin barrier function by +30% in 1 hour."
Morning
Evening
Dry & dehydrated skin
Total Moisture Daily Facial Cream™ AM/PM Multi-Layered Moisturisation with H.E.O.® & Prebiotic Peptides
Full Size (50ml) | £50
A clear glass dropper bottle of Liquid Peptides serum is presented, with its dropper removed and resting beside it and serum droplets, showing the texture.
Woman is applying Liquid Peptides serum with a dropper to their face. To the left, text states "VISIBLE RESULTS IN JUST 7 DAYS*" and lists benefits: wrinkles smoothed, youthful-looking skin, improved skin firmness, increased skin plumpness, hydration restored. A footnote indicates the claims are proven via an independent consumer study.
Morning
Evening
Fine lines & wrinkles
Liquid Peptides™ 30% Complex Multi-Peptide Age-Defying Serum
Full Size (30ml) | £59
A tube of Eyelift Peptides stands upright, with a swatch of the product behind it.
A tube of Eyelift Peptides is displayed. Four bullet points with checkmarks list benefits: Visibly lifts eye contours & smooths fine lines, Reduces the look of dark circles & puffiness, Hydrates & comforts the delicate eye area, and Creates the ideal smoothing base for makeup.
Evening
Fine lines & wrinkles
Eyelift™ Peptides Age-Defying Firming Gel
Full Size | £45
Medik8 Advanced Pro-Collagen+ Peptide Cream jar with a closed silver lid, centered on a clean white background. The frosted glass jar displays text highlighting "Rejuvenating Anti-Wrinkle Moisturiser with GF MiniProtein & NAD+ Boost.
Black backdrop with the Advanced Pro-Collagen+ Peptide Cream jar and text reading: 'Helps to increase collagen production by 45%*.' Benefit claims include firmer skin, reduced wrinkles, and increased elasticity. Asterisk notes this is from an ex vivo study.
Morning
Evening
Advanced Pro-Collagen+ Peptide Cream (Travel size) Rejuvenating Anti-Wrinkle Moisturiser With GF MiniProteinTM & NAD+ Longevity Booster
Travel Size (12.5ml) | £27
A purple glass dropper bottle of Bakuchiol Peptides serum, with its dropper removed. A swirl of the serum is shown, emphasising the product's texture.
A purple glass dropper bottle of Bakuchiol Peptides serum is shown with its dropper. To the left, text highlights the product as a "PLANT-BASED RETINOL ALTERNATIVE" with benefits including: smoothing fine lines & wrinkles, visibly evening skin tone & texture, calming, plumping & brightening skin's appearance, and being suitable for use while pregnant/nursing.
Morning
Evening
Fine lines & wrinkles
Bakuchiol Peptides™ Retinol Alternative Peptide-Infused Serum
Full Size (30ml) | £55
Two small white bottles of Oxy-R Peptides serum are displayed. A black dropper tool lies nearby, and two drops of yellow serum are visible on the white surface
Two small white bottles of Oxy-R Peptides are displayed with drops of yellow serum. Text highlights PROFESSIONAL STRENGTH ACTION ON DARK SPOTS. Benefits listed are: Delivers brighter, more even skin in just 7 days, Fades visible dark spots in 1 month, Effective on all skin types & tones, and Hydrates & smooths the complexion.
Morning
Evening
Hyperpigmentation
Oxy-R Peptides™ High-Strength Oxyresveratrol Brightening Peptide Serum
Full Size (2 x 10ml) | £65
Total Moisture Daily Facial Cream™ (Travel size)
Total Moisture Daily Facial Cream™ (Travel size)
Morning
Evening
Total Moisture Daily Facial Cream™ (Travel size) AM/PM Multi-Layered Moisturisation with H.E.O.® & Prebiotic Peptides
Travel Size (12.5ml) | £16
Liquid Peptides Try Me - With Carton - Grey Background
Liquid Peptides™ (Travel Size)
Morning
Evening
Liquid Peptides™ (Travel Size) 30% Complex Multi-Peptide Serum
Travel Size (8ml) | £20
Advanced Pro-Collagen+ Peptide Cream Refill
Black backdrop with the Advanced Pro-Collagen+ Peptide Cream jar and text reading: 'Helps to increase collagen production by 45%*.' Benefit claims include firmer skin, reduced wrinkles, and increased elasticity. Asterisk notes this is from an ex vivo study.
Morning
Evening
Fine lines & wrinkles
Advanced Pro-Collagen+ Peptide Cream Refill Rejuvenating Anti-Wrinkle Moisturiser With GF MiniProteinTM & NAD+ Longevity Booster
£74
Total Moisture Daily Facial Cream Refill™
An open frosted glass jar of Medik8 Total Moisture Daily Facial Cream with a peak of white cream on top, set against a clean white background. Badges in the top corners indicate it is a "Daisy Beauty Awards Vinnare 2025" (Winner) and "Dermatologist Recommended."
Morning
Evening
Dry & dehydrated skin
Total Moisture Daily Facial Cream Refill™ AM/PM Multi-Layered Moisturisation with H.E.O.® & Prebiotic Peptides
Full Size (50ml) | £43

Frequently Asked Questions

How often and when should you apply peptides in your skincare routine?

Peptides are gentle enough for daily use and can be applied both morning and evening after cleansing. Use a peptide serum before your moisturiser, or opt for a peptide-rich cream if you prefer a simplified routine.

Medik8’s Liquid Peptides Advanced MP is a lightweight, fast-absorbing serum that delivers targeted, clinical-grade peptide technology to visibly smooth expression lines and improve skin firmness, suitable for all skin types. If you're looking to visibly brighten the complexion and reduce the appearance of dark spots or post-blemish marks, Oxy-R Peptides is a targeted formula suitable for all skin tones.

What are the benefits of peptides for the skin?
Peptides support collagen and elastin production to help improve firmness and elasticity. With consistent use, peptides can help reduce the appearance of fine lines, smooth texture, and boost overall skin resilience. They also work to strengthen the skin barrier, enhancing hydration and reinforcing the skin’s natural defences for a plumper, more radiant complexion.

What do peptides do for the under-eyes?

Peptides help to support the delicate skin under the eyes by encouraging collagen production and strengthening the skin barrier. This can reduce the appearance of fine lines, improve firmness and minimise puffiness over time. The gentle nature of peptides makes them ideal for this sensitive area, helping to restore a smoother, more refreshed look.

Which peptides are best for anti-ageing?

Different peptides target different signs of ageing, which is why combining them often delivers the most visible results. Signal peptides help stimulate collagen production, while neurotransmitter peptides visibly smooth expression lines. Carrier peptides support skin regeneration, and enzyme-inhibitor peptides help slow the breakdown of collagen and elastin.

Medik8’s Liquid Peptides Advanced features a 30% blend of 10 carefully selected peptides, including our pioneering Dual MiniProteins™. This next-generation formula is clinically proven to visibly reduce both expression lines and deeper wrinkles, offering comprehensive, targeted support for firmer, smoother-looking skin[1].

[1]To verify visit: https://www.medik8.com/pages/circana-group-claim-letters-liquid-peptides-advanced-mp

Can you use peptides with vitamin C?

Peptides can be used with vitamin C without any issues. Vitamin C brightens and protects the skin, while peptides work to improve skin firmness and smoothness. Together, they offer a complementary approach to ageing concerns, helping to promote a radiant and resilient complexion. Apply vitamin C in the morning, followed by a peptide serum or moisturiser such as Daily Radiance Vitamin C or Clarity Peptides.

What is the best age to start peptide serum?

Peptides can be introduced into your skincare routine from your mid-20s onwards, when collagen production naturally begins to decline. They’re a great way to support the skin early on, helping to maintain firmness and prevent the early signs of ageing, without the need for stronger active ingredients.

What not to mix peptides with?

Peptides are generally well-tolerated and pair well with most skincare ingredients. However, it's best to avoid using them alongside high concentrations of low pH acids, such as strong AHAs or vitamin C, as this may reduce their effectiveness. If you're using both, alternate them between your morning and evening routines to get the full benefit.

When should you apply peptides in your skincare routine?

Peptides can be applied in both the morning and evening after cleansing. Apply a peptide serum before your moisturiser, or choose a peptide-rich cream that can be used on its own. Medik8’s Liquid Peptides Advanced is a lightweight, fast-absorbing formula suitable for all skin types. For those looking to target uneven skin tone, Oxy-R Peptides helps to visibly brighten the complexion and reduce dark spots and post-blemish marks.

At what age should you start using peptide skincare products?
Peptides can benefit skin at any age, but they're particularly valuable from your mid-twenties onwards when natural collagen production begins to decline. Starting peptide treatments early helps maintain skin firmness and prevent premature signs of ageing. However, peptides are equally effective for mature skin, helping to restore elasticity and smooth existing lines and wrinkles through enhanced collagen synthesis.

Can you use peptides when pregnant?

Peptides are generally considered safe to use during pregnancy. Unlike ingredients such as retinoids, peptides do not pose known risks and can continue to support the skin through hydration and repair. However, if you’re unsure, it’s always best to check with a healthcare provider.

Can you use peptides with retinol?

Peptides and retinol aren’t rivals, they’re complementary. While retinol encourages skin renewal and boosts collagen production, it can sometimes cause dryness or irritation, particularly for sensitive skin. Peptides, on the other hand, help to firm, smooth and support the skin barrier more gently.

Using both in a balanced routine can deliver powerful results. Peptides can help buffer the effects of retinol, making the combination ideal for visibly improving signs of ageing without compromising comfort. 

Medik8’s Crystal Retinal pairs well with Liquid Peptides in a balanced evening routine.

Are peptides suitable for sensitive skin?
Yes, peptides are generally very well tolerated, even by sensitive skin. Their gentle nature makes them ideal for supporting skin that’s prone to irritation, as they help to calm, hydrate and reinforce the skin barrier. As with any new product, we recommend patch testing first, especially if your skin is reactive or compromised.

Which types of peptides are most effective?

Peptides are a diverse group of active ingredients, each designed to target specific skin concerns. 

  • Signal peptides help stimulate collagen production, 
  • Carrier peptides support skin repair
  • Neurotransmitter peptides work to visibly soften the appearance of expression lines.

The most advanced formulations combine multiple peptide types to deliver comprehensive anti-ageing benefits and support overall skin renewal.

Liquid Peptides Advanced is Medik8’s next-generation peptide serum, formulated with a 30% multi-peptide blend and powered by Dual MiniProteins™ to visibly target both early and deep-set wrinkles.

At what age should you start using peptide skincare products?
Peptides can benefit skin at any age, but they're particularly valuable from your mid-twenties onwards when natural collagen production begins to decline. Starting peptide treatments early helps maintain skin firmness and prevent premature signs of ageing. However, peptides are equally effective for mature skin, helping to restore elasticity and smooth existing lines and wrinkles through enhanced collagen synthesis.

Can you use peptides when pregnant?

Peptides are generally considered safe to use during pregnancy. Unlike ingredients such as retinoids, peptides do not pose known risks and can continue to support the skin through hydration and repair. However, if you’re unsure, it’s always best to check with a healthcare provider.

Can you use peptides with retinol?

Peptides and retinol aren’t rivals, they’re complementary. While retinol encourages skin renewal and boosts collagen production, it can sometimes cause dryness or irritation, particularly for sensitive skin. Peptides, on the other hand, help to firm, smooth and support the skin barrier more gently.

Using both in a balanced routine can deliver powerful results. Peptides can help buffer the effects of retinol, making the combination ideal for visibly improving signs of ageing without compromising comfort. 

Medik8’s Crystal Retinal pairs well with Liquid Peptides in a balanced evening routine.

Can you use peptides with vitamin C?

Peptides can be used with vitamin C without any issues. Vitamin C brightens and protects the skin, while peptides work to improve skin firmness and smoothness. Together, they offer a complementary approach to ageing concerns, helping to promote a radiant and resilient complexion. Apply vitamin C in the morning, followed by a peptide serum or moisturiser such as Daily Radiance Vitamin C or Clarity Peptides.

What is the best age to start peptide serum?

Peptides can be introduced into your skincare routine from your mid-20s onwards, when collagen production naturally begins to decline. They’re a great way to support the skin early on, helping to maintain firmness and prevent the early signs of ageing, without the need for stronger active ingredients.

What not to mix peptides with?

Peptides are generally well-tolerated and pair well with most skincare ingredients. However, it's best to avoid using them alongside high concentrations of low pH acids, such as strong AHAs or vitamin C, as this may reduce their effectiveness. If you're using both, alternate them between your morning and evening routines to get the full benefit.

Are peptides suitable for sensitive skin?
Yes, peptides are generally very well tolerated, even by sensitive skin. Their gentle nature makes them ideal for supporting skin that’s prone to irritation, as they help to calm, hydrate and reinforce the skin barrier. As with any new product, we recommend patch testing first, especially if your skin is reactive or compromised.

Which types of peptides are most effective?

Peptides are a diverse group of active ingredients, each designed to target specific skin concerns. 

  • Signal peptides help stimulate collagen production, 
  • Carrier peptides support skin repair
  • Neurotransmitter peptides work to visibly soften the appearance of expression lines.

The most advanced formulations combine multiple peptide types to deliver comprehensive anti-ageing benefits and support overall skin renewal.

Liquid Peptides Advanced is Medik8’s next-generation peptide serum, formulated with a 30% multi-peptide blend and powered by Dual MiniProteins™ to visibly target both early and deep-set wrinkles.

Shop by Peptides

Skin-signalling science

Peptides are short chains of essential amino acids that act as messengers, signalling the skin to boost firmness, smoothness, and visible elasticity. By targeting expression lines and loss of tone, they offer a refined approach to age-defying skincare.

Flexible, routine-friendly performance

Suitable for both morning and evening use, peptide serums layer easily after cleansing and before moisturiser. For restorative results, peptides and retinal are a dream duo. Our Liquid Peptides Advanced MP makes a perfect pairing with Crystal Retinal to support a more youthful-looking complexion. Prefer a clarifying finish? Niacinamide Peptides combines 10% niacinamide with peptides to refine the look of pores and smooth congested texture, leaving oily and blemish-prone skin with a fresh, glass-like glow.

Developed with clinical integrity

Our peptide range has been developed using advanced, precision technologies tailored to each formula. From our proprietary MiniProteins™ for enhanced performance, to multi-peptide complexes featuring Matrixyl and carnosine, every product is backed by clinical insight to help visibly improve your skin and its individual needs.