Skincare Bestsellers

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Discover our most-loved skincare formulas, expertly developed to deliver visible results across a range of skin concerns. From advanced serums to nourishing moisturisers and everyday essentials, explore the tried-and-loved formulas our customers come back to time and again. Whether you’re building a new regime or searching for your next skincare favourite, start with our bestselling formulas.

 
Liquid Peptides Advanced MP & Exo-PDRN Prismatic+ Bundle
Liquid Peptides Advanced MP & Exo-PDRN Prismatic+ Bundle
Morning
Evening
Deep Set Lines & Wrinkles
Liquid Peptides Advanced MP & Exo-PDRN Prismatic+ Bundle Lifting & Rejuvenating Duo
£136.85
Crystal Retinal®
Crystal Retinal®
Evening
Fine Lines & Wrinkles
Crystal Retinal® Award-winning Age-Defying Vitamin A Night Serum
Full Size (30ML) | £45
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Liquid Peptides Advanced MP
Liquid Peptides Advanced MP
Morning
Evening
Deep Set Lines & Wrinkles
Liquid Peptides Advanced MP Wrinkle reduction serum with 30% multi-peptide complex - proven to deliver results in as little as 10 minutes.¹
Full Size (30ml) | £82
Medik8 Advanced Night Restore cream jar shown open with a rich dollop of white cream peaked on top against a clean white background, highlighting its smooth, restorative texture. Black text on the jar reads "Rejuvenating Multi-Ceramide Night Cream".
A model applies Medik8 Advanced Night Restore, smiling with a dab of cream on her cheek while holding the jar. Text lists benefits including "100% agreed their skin looks firmer after 4 weeks*" and "90% agreed this is their go to night cream."
Evening
Fine Lines & Wrinkles
Advanced Night Restore™ Rejuvenating Multi-Ceramide Night Cream
Full Size (50ml) | £62
Medik8 C-Tetra Advanced bottle displayed on a clean white background with translucent serum droplets, highlighting its lightweight gel-serum texture.
Close-up of a woman with radiant, even-toned skin, with text highlighting how C-Tetra Advanced defends against premature ageing by improving brightness, wrinkles, and skin texture.
Morning
Fine Lines & Wrinkles
C-Tetra® Advanced 20% Vitamin C Gel-Serum With Phyto Exosomes
Full Size (30ml) | £72
Wrinkle Reduction, Redefined

Wrinkle Reduction, Redefined

Liquid Peptides Advanced MP

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An open jar of Medik8 Advanced Pro-Collagen+ Peptide Cream displaying a swirl of white cream on a clean white background. Text on the jar describes it as a "Rejuvenating Anti-Wrinkle Moisturiser with GF MiniProtein & NAD+ Boost". A graphic in the top left corner highlights "GF MINIPROTEINS™ & NAD+ LONGEVITY BOOSTER".
Black backdrop with the Advanced Pro-Collagen+ Peptide Cream jar and text reading: 'Helps to increase collagen production by 45%*.' Benefit claims include firmer skin, reduced wrinkles, and increased elasticity. Asterisk notes this is from an ex vivo study.
Morning
Evening
Fine Lines & Wrinkles
Advanced Pro-Collagen+ Peptide Cream Rejuvenating Anti-Wrinkle Moisturiser With GF MiniProteinTM & NAD+ Longevity Booster
Full size (50ml) | £82
Exo-PDRN Prismatic+
A close-up of a smiling woman applying a clear drop of serum to her cheek. Text reads "Full-Spectrum Rejuvenation Results" next to a checklist with checkmarks for: Skin Health, Volume, Luminosity, Skin Tone, Wrinkles, and Firmness.
Morning
Evening
Dullness
Exo-PDRN Prismatic+ Youthful Vitality Serum with Prismatic PDRN & Triple Exosome Complex
Full size (30ml) | £79
Festive Kit
Rejuvenation Routine
Three Medik8 products wrapped in a red ribbon against a deep red background, with text highlighting key benefits for each. The Exo-PDRN Prismatic+ deluxe sample "Supports visibly enhanced skin luminosity & resilience," the Daily Radiance Vitamin C jar "Hydrates, brightens & protects with SPF 30," and the Crystal Retinal 3 tube "Visibly firms, brightens & smooths the skin."
Rejuvenation Routine Protecting & Renewing Essentials
£85
Festive Kit
Medik8 Retinal Recharge skincare set featuring a white and blue gift box with two tubes - a Crystal Retinal 3 tube and Crystal Retinal Ceramide Eye 3 tube, and a dark blue ribbon, with a 'SAVING £28' promotional badge on a dark blue background.
Two Medik8 products wrapped in a dark blue ribbon against a dark blue background, with text highlighting key benefits for each. The Crystal Retinal 3 tube "Visibly firms, brightens & smooths the skin," and the Crystal Retinal Ceramide Eye 3 tube "Targets visible crow's feet, fine lines & puffiness."
Evening
Retinal Recharge Age-Defying Face & Under Eye Duo
£64
Festive Kit
Moisture Minis
Two Medik8 travel size products stacked and wrapped in a teal ribbon against a teal background, with text highlighting key benefits for each. The top Daily Radiance Vitamin C jar "Hydrates, brightens & protects with SPF 30," and the bottom Advanced Night Restore jar "Replenishes moisture & supports the skin barrier."
Moisture Minis Protecting & Nourishing Duo
£28
Festive Kit
Medik8 Age-Defying Essentials gift set featuring skincare products including Crystal Retinal, Advanced Pro-Collagen+ Peptide Cream, and Liquid Peptides Advanced MP Deluxe Sample, presented in a white box with blue ribbons on a dark blue background. A 'Saving £38' promotional badge is visible in the top left.
Three Medik8 products wrapped in a blue ribbon against a dark blue background, with text highlighting key benefits for each. The Crystal Retinal 6 tube "Visibly firms, brightens & smooths the skin," the Liquid Peptides Advanced MP deluxe sample "Delivers advanced deep-set wrinkle reduction," and the Advanced Pro-Collagen+ Peptide Cream jar "Supports visible skin firmness & elasticity."
Age-Defying Essentials Ultimate Skin Renewing Heroes
£113
Festive Kit
Nighttime Nourish
Two Medik8 products wrapped in a green ribbon against a dark green background, with text highlighting key benefits for each. The Crystal Retinal 3 tube "Visibly firms, brightens & smooths the skin," and the Advanced Night Restore travel size jar "Replenishes moisture & supports the skin barrier."
Nighttime Nourish Firming & Renewing Duo
£49
Festive Kit
Radiance Ritual
Four Medik8 products displayed against a burnt orange background with an orange ribbon, with text pointing to key benefits for each. Advanced Day Ultimate Protect tube "Protects against UV rays & environmental stressors," C-Tetra Luxe serum bottle "Boosts visible radiance & deeply nourishes the skin," Total Moisture Daily Facial Cream jar "Hydrates, plumps & supports the skin barrier," and Hydr8 B5 Intense serum bottle "Delivers supercharged, long-lasting hydration."
Radiance Ritual Brightening & Hydrating Heroes
£67
Total Moisture Daily Cleansing Gel
Total Moisture Daily Cleansing Gel
Morning
Evening
Dry & dehydrated skin
Total Moisture Daily Cleansing Gel Barrier-Boosting Gel-to-Foam with Moisture MagnetsTM & Prebiotics
Full Size (145ml) | £29
Medik8 Crystal Retinal Ceramide Eye 3 cream tube next to a zigzag swatch of yellow cream on a white background. Two silver badges highlight "WINNER OF 4+ GLOBAL AWARDS" and "WORLD FIRST PATENTED TECHNOLOGY".
A woman's face is shown with small dots of Crystal Retinal Ceramide Eye applied under one eye. Text highlights WORLD'S 1st CLINICAL STRENGTH RETINAL FOR UNDER EYES. Three bullet points with checkmarks list benefits: Visibly brightens, smooths & lifts the eye area, Plumps the eye area overnight, and Reduces the look of puffiness.
Evening
Fine Lines & Wrinkles
Crystal Retinal® Ceramide Eye Smooth & Lift Eye Cream Gentle-Release Vitamin A
Crystal Retinal Ceramide Eye 3 (15ml) | £42
Medik8 Lipid-Balance Cleansing Oil bottle stands against a white background. Golden oil droplets surround the bottle, highlighting its rich, fluid texture.
Lipid-Balance Cleansing Oil bottle stands on a white block. Text lists benefits including removing heavy makeup, supporting the lipid barrier, and acting as a transformative oil-to-milk cleanser.
Evening
Dry & dehydrated skin
Lipid-Balance Cleansing Oil™ Make-Up Dissolving Oil-to-Milk
Purifying Moringa & Omega-6
Full Size (140ml) | £35
Medik8 Hydr8 B5 Intense glass dropper bottle in deep purple, shown with an open pipette resting above light pink serum droplets on a clean white background. Text highlights the formula as Hyaluronic Acid with NMF (Natural Moisturising Factors) to Replenish & Boost in a 30mL size.
A split-screen image showing a model applying serum with a dropper alongside a list of benefits on a textured purple background. Text claims that 100% showed visibly hydrated skin, improves skin hydration both instantly and over time, and protects against dehydrating changes in the environment.
Morning
Evening
Fine Lines & Wrinkles
Hydr8 B5™ Intense Supercharged Multi-Weight Hyaluronic Acid Serum with NMF
Full Size (30ml) | £60
Medik8 Niacinamide Peptides serum bottle with a white pump top, resting on a white surface with a smear of white serum behind it.
A split image showing a close-up of skin texture labelled "Before" and "After 4 Weeks," highlighting improvements. Text on the left lists benefits: "Reduced blemishes," "Improved skin texture," "Reduced pore size," and "Soothed visible redness."
Morning
Evening
Enlarged pores & blemishes
Niacinamide Peptides 10% Niacinamide Serum with Peptides & NAG
Full size (30ml) | £49
Medik8 Daily Radiance Vitamin C glass cream jar is shown open with a generous peak of pale yellow cream on top. Text identifies the product as a 50mL C-Tetra Cream SPF 30 Two-in-One Moisturiser.
"A model with glowing skin smiles next to a list of product benefits on a soft gold background. Text highlights the 2-in-1 Vitamin C Moisturiser with SPF 30: "Prevents signs of premature ageing, Boosts skin radiance, Hydrates the complexion, 100% agree their skin feels protected all day*"
Morning
Dullness
Daily Radiance Vitamin C™ C-Tetra 7% Vitamin C Cream SPF 30 Two-in-One Moisturiser
Full Size (50ml) | £62
Medik8 C-Tetra Luxe serum bottle shown open with its glass pipette resting against the rim, displayed on a white background with clear, translucent serum droplets. The image includes a "GET THE GLOSS BEAUTY AWARDS GOLD 2024" seal in the top left and a "DERMATOLOGIST RECOMMENDED" emblem with a magnifying glass icon in the top right.
Close-up of a smiling woman with glowing skin on a warm orange background. Text reads: ‘Clinically proven to: Healthy glow in just 1 use*. Reduces visible wrinkles and hyperpigmentation in 4 weeks*. Helps to strengthen your skin barrier.’
Morning
Fine Lines & Wrinkles
C-Tetra® Luxe Lipid 14% Vitamin C Enhanced Radiance Serum
Full Size (30ml) | £62
A white tube of Advanced Day Ultimate Protect stands upright, with a swipe of light cream behind it.
Advanced Day Ultimate Protect™
Morning
Fine Lines & Wrinkles
Advanced Day Ultimate Protect™ Age-Defying Moisturiser with Photolyase SPF 50+ | PA++++
Full Size (50ml) | £59
Medik8 Hydr8 B5 serum bottle stands against a clean white background with a clear liquid puddle and droplets, with the dropper resting on top. Text identifies the product as a 30mL "Liquid Rehydration Serum."
Medik8 Hydr8 B5 serum bottle stands on a white pedestal against a bright white background. Text highlights that the product "Delivers long-lasting skin hydration," "Helps the skin retain essential moisture," "Softens the look of fine lines & wrinkles," and "Promotes a visibly plump & supple complexion."
Morning
Evening
Dry & dehydrated skin
Hydr8 B5™ Liquid Rehydration Serum
Full Size (30ml) | £45
Medik8 Surface Radiance Cleanse tube displayed on a clean white background with a large, translucent gel texture smear. Text identifies it as a Resurfacing AHA/BHA Mangosteen Cleansing Gel in a 150mL size.
Medik8 Surface Radiance Cleanse tube on a bright background with checkmark graphics. Text highlights its benefits: brightening and exfoliating acids for a youthful glow, refreshing and smoothing gel-to-light foam formula, smooths fine lines and wrinkles, and antioxidant-infused for healthy-looking skin.
Morning
Evening
Dullness
Surface Radiance Cleanse™ Smoothing Gel-to-Foam
Exfoliating AHA/BHA
Full Size (150ml) | £25
An open frosted glass jar of Medik8 Total Moisture Daily Facial Cream with a peak of white cream on top, set against a clean white background. Badges in the top corners indicate it is a "Daisy Beauty Awards Vinnare 2025" (Winner) and "Dermatologist Recommended."
An image split between a white cream texture background and a smiling woman touching her radiant face. Text highlights key benefits with checkmarks: "Infuses moisture into the lowest layers of your skin," "Instantly plumps and softens your skin," and "Clinically proven to boost skin barrier function by +30% in 1 hour."
Morning
Evening
Dry & dehydrated skin
Total Moisture Daily Facial Cream™ AM/PM Multi-Layered Moisturisation with H.E.O.® & Prebiotic Peptides
Full Size (50ml) | £50
Medik8 Press & Glow tonic bottle stands against a clean white background with translucent liquid droplets and a puddle, highlighting its watery texture. Text identifies the product as a 200mL "Daily Exfoliating PHA Tonic with Enzyme Activator."
A circular, light beige badge displaying the "Sheerluxe Beauty Awards" logo in black text, with "Shortlisted 2024" highlighted in red at the bottom.
Morning
Evening
Dullness
Press & Glow® Brightening 5.5% PHA Tonic
Gluconolactone & Enzyme Activator
Full Size (200ml) | £34
A bottle of Medik8 C-Tetra Lipid Vitamin C Radiance Serum open with its dropper resting diagonally across the top. Set against a clean white background, the bottle is surrounded by three clear puddles of serum, showcasing its liquid texture.
Close-up portrait of a woman with her eyes closed, showcasing a bright and even skin tone. Text highlights that the product "Restores the look of skin radiance in 7 days," delivers a visibly brighter tone, and increases skin youthfulness.
Morning
Dullness
C-Tetra® Lipid 7% Vitamin C Radiance Serum
Full Size (30ml) | £45
Medik8 Super C Ferulic serum bottle shown open with its glass pipette resting against the rim, displayed on a clean white background with translucent serum droplets. The amber glass bottle features the Medik8 logo and is labeled "SUPER C FERULIC Potent Vitamin C Brightening Serum" in a 30mL size.
Close-up of a person's face being treated with a glass pipette, set against a light grey background. Text states the product is "CLINICALLY PROVEN ACTION ON 4 SIGNS OF SUN AGEING*" followed by four check-marked claims: Visibly reduces dark spots & age spots*, Improves the look of fine lines & wrinkles in just 4 weeks*, Increases skin firmness & elasticity in 4 weeks*, and Visibly evens the skin tone*. A footer note specifies these results are proven via an independent clinical study.
Morning
Deep Set Lines & Wrinkles
Super C Ferulic™ Potent 30% Vitamin C Brightening Serum
Full Size (30ml) | £69
A tube of Eyelift Peptides stands upright, with a swatch of the product behind it.
A tube of Eyelift Peptides is displayed. Four bullet points with checkmarks list benefits: Visibly lifts eye contours & smooths fine lines, Reduces the look of dark circles & puffiness, Hydrates & comforts the delicate eye area, and Creates the ideal smoothing base for makeup.
Morning
Evening
Fine Lines & Wrinkles
Eyelift™ Peptides Age-Defying Firming Gel
Full Size | £45
Medik8 Press & Clear bottle (150ml) displayed on a white background with splashes of blue tonic around it. Text highlights the "Exfoliating 2% BHA Tonic" formula.
A model applies toner with a cotton pad alongside text listing "Proven Results," including "7 days to clarified, healthier-looking skin*" and "38% reduction in visible blemishes**".
Morning
Evening
Enlarged pores & blemishes
Press & Clear™ Pore-Refining 2% BHA Tonic
Encapsulated Salicylic Acid
Full Size (150ml) | £35
Medik8 Micellar Mousse pump bottle displayed on a white background with a smear of white foam behind it, highlighting the product's texture.
A split image featuring the foam texture application alongside a list of benefits, including "Removes makeup, sunscreen & impurities" and "Purifies & Nourishes the skin."
Morning
Evening
Redness
Micellar Mousse™ Purifying & Nourishing Effortless Rinse-Off Cleanser
Full Size (150ml) | £25
Medik8 Clarifying Foam pump bottle displayed on a clean white background with three dollops of white airy foam. Text identifies it as a Refreshing AHA/BHA Blemish Cleanser in a 150mL size.
Medik8 Clarifying Foam being dispensed into a palm, shown next to a list of benefits on a bubbly white background. Text highlights its pH-balanced formula that visibly smooths, clarifies, and decongests the skin; reduces the look of blemishes; prevents future blemishes; and leaves skin calm and balanced.
Morning
Evening
Blemishes
Clarifying Foam™ Refreshing AHA/BHA Blemish Cleanser
Full Size (150ml) | £25
A sleek white pump bottle of r-Retinoate Day & Night stands upright, with a swirl of white cream next to it.
A woman's face is shown with a small amount of white cream on their cheek. Four bullet points with checkmarks list benefits: Visibly brightens, revitalises & smooths the skin; For results 8x more powerful than retinol* – both day & night; Improves uneven skin tone & texture; and a 3-in-1 serum for a simplified regime.
Morning
Evening
Fine Lines & Wrinkles
r-Retinoate® Day & Night Youth Activating Cream
Full Size (50ml) | £149
The two tubes of Medik8 H.E.O. Mask are displayed: a blue tube for Step 1 with a blue gel swatch, and a white tube for Step 2 with a white cream swatch.
A woman smiling while holding the two tubes of Medik8 H.E.O. Mask (blue Step 1 and white Step 2). Text highlights the product as a CLINICALLY PROVEN 2-STEP OVERNIGHT MASK with benefits including: 72 hours of skin hydration & moisture retention, 72 hours of skin barrier support, visibly reduces fine lines, flakiness & crepiness, and delivers plump, glowing, supple-looking skin.
Evening
Dry & dehydrated skin
H.E.O.® Mask Optimal Ratio Moisturisation Two-Step Overnight Mask
Full Size (50 ml x 2) | £60
Total Moisture Daily Facial Cream Refill™
An open frosted glass jar of Medik8 Total Moisture Daily Facial Cream with a peak of white cream on top, set against a clean white background. Badges in the top corners indicate it is a "Daisy Beauty Awards Vinnare 2025" (Winner) and "Dermatologist Recommended."
Morning
Evening
Dry & dehydrated skin
Total Moisture Daily Facial Cream Refill™ AM/PM Multi-Layered Moisturisation with H.E.O.® & Prebiotic Peptides
Full Size (50ml) | £43

Frequently Asked Questions

What are Medik8’s best-selling products?

Medik8’s most popular products include the Crystal Retinal range, known for delivering effective anti-ageing results with minimal irritation. Our C-Tetra Advanced is a new favourite, praised for brightening, evening and protecting skin. The Hydr8 B5 Intense serum is also a top seller, offering deep hydration and improved skin barrier support.

Which Medik8 products should I use?

A simple Medik8 routine is built around our CSA Philosophy: Vitamin C and sunscreen by day, Vitamin A by night. Start your morning with Surface Radiance Cleanser to gently refresh, followed by C Tetra Advanced to deliver powerful brightening and antioxidant protection. Then lock in hydration with a moisturiser and broad-spectrum SPF 30. In the evening, after cleansing and toning, reach for our vitamin A night serum Crystal Retinal to visibly smooth fine lines and support skin renewal overnight.

What makes Medik8 products different from other skincare brands?
Medik8 is an award-winning, age-defying skincare brand that takes a science-led approach with a commitment to proven, effective ingredients. Our CSA Philosophy simplifies skincare and is clinically proven to deliver youthful, glowing skin. We believe in using vitamin C plus sunscreen in the morning and vitamin A (also known as retinol/retinal) at night. As a certified B Corp, Medik8 meets verified standards for social and environmental business practices.

How long before I see results with Medik8 products?
Results vary depending on the product and your skin’s condition, but many users start noticing improvements within 2 to 4 weeks. For anti-ageing benefits, such as reduced fine lines and improved texture, it can take 6 to 12 weeks of consistent use to see significant changes. With active ingredients like retinal and Vitamin C, patience and regular application are key to achieving the best results.

Bestsellers

Our skincare bestsellers aren't shaped by trends. Each formula earns its place through rigorous clinical testing, stabilised high-performance ingredients and delivery technologies designed to ensure actives reach exactly where they're needed. 

From Crystal Retinal, the number one retinal serum worldwide, to Advanced Day Ultimate Protect, a multi-award winning SPF 50+ moisturiser, every bestseller reflects Medik8's commitment to Results Without Compromise.

Tried, tested and trusted

Our most-loved formulas are backed by independent consumer and clinical studies, with results verified across a range of skin types and tones. Explore clinical trials and skincare awards to understand the evidence behind the products, or visit our skincare resources to find the right formula for your skin.