Medik8 r-Retinoate Intense Youth Activating Cream bottle displayed on a white background with a swatch of the peach-toned cream texture visible behind it.
A person with a streak of cream on their cheek holds a bottle of Medik8 r-Retinoate Intense. Claims include 8x more powerful and 11x faster than classic retinol, with dramatic wrinkle and dark spot reduction in 4 weeks.
A person holds a bottle of Medik8 r-Retinoate Intense. Text states that 91% of participants agreed their skin looked instantly smoother after just 1 use.
Medik8 r-Retinoate Intense cream bottle against a dark feathered background. Text highlights 5 age-defying technologies: Encapsulated Retinyl Retinoate, Retinal, Ceramide Complex, Drone-Targeted Peptide, and Hyaluronic Acid.
Three Medik8 r-Retinoate products displayed on a reflective surface: r-Retinoate Day & Night and r-Retinoate Day & Night Eye Serum (both for AM/PM use), and r-Retinoate Intense (for PM use only).
Infographic titled "HOW TO LAYER" showing a PM routine: Medik8 Lipid-Balance Cleansing Oil for Cleanse, Press & Glow for Tone, r-Retinoate Eye for Eyes, and r-Retinoate Intense for Vitamin A. Expert advice notes to always wear sunscreen the following morning.
Medik8 r-Retinoate Intense Youth Activating Cream bottle stands next to its black outer packaging, which features white hexagonal chemical structure graphics and a textured wavy pattern.
Medik8 r-Retinoate Intense Youth Activating Cream bottle displayed on a white background with a swatch of the peach-toned cream texture visible behind it.
A person with a streak of cream on their cheek holds a bottle of Medik8 r-Retinoate Intense. Claims include 8x more powerful and 11x faster than classic retinol, with dramatic wrinkle and dark spot reduction in 4 weeks.
A person holds a bottle of Medik8 r-Retinoate Intense. Text states that 91% of participants agreed their skin looked instantly smoother after just 1 use.
Medik8 r-Retinoate Intense cream bottle against a dark feathered background. Text highlights 5 age-defying technologies: Encapsulated Retinyl Retinoate, Retinal, Ceramide Complex, Drone-Targeted Peptide, and Hyaluronic Acid.
Three Medik8 r-Retinoate products displayed on a reflective surface: r-Retinoate Day & Night and r-Retinoate Day & Night Eye Serum (both for AM/PM use), and r-Retinoate Intense (for PM use only).
Infographic titled "HOW TO LAYER" showing a PM routine: Medik8 Lipid-Balance Cleansing Oil for Cleanse, Press & Glow for Tone, r-Retinoate Eye for Eyes, and r-Retinoate Intense for Vitamin A. Expert advice notes to always wear sunscreen the following morning.
Medik8 r-Retinoate Intense Youth Activating Cream bottle stands next to its black outer packaging, which features white hexagonal chemical structure graphics and a textured wavy pattern.
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r-Retinoate® Intense

  • Rejuvenate
  • |
  • Firm
  • |
  • Brighten
Intense Youth Activating Cream

Setting new standards for age-defying excellence, r-Retinoate Intense is the jewel in the Medik8 Vitamin A crown.

Proven to deliver noticeably firmer, smoother, brighter-looking skin, with dramatic wrinkle and dark spot reduction in as little as 4 weeks.*

Also proven to be 8x stronger** and 11x faster^ than classic retinol, this innovative vitamin A formula is powered by a revolutionary blend of retinal and encapsulated retinyl retinoate (exclusive to Medik8).

Combining 5 of Medik8's most advanced age-defying technologies in 1 extraordinary nighttime cream, r-Retinoate Intense delivers everything your skin needs for astonishing youth-renewing results in one simple but luxurious step.

Please Note: Product packaging shown may be different to the product received due to regional variations

*Proven via independent consumer study on r-Retinoate Intense on 52 participants over 4 weeks. **H. Kim et al., Synthesis and in vitro biological activity of retinyl retinoate, a novel hybrid retinoid derivative, Bioorganic & Medicinal Chemistry, 2008, 15;16(12), pp 6387-93 ^G. Siegenthaler et al., Retinol and retinal metabolism, Biochemical Journal, 1990, 268, pp 371-378.
Full Size (50ML)
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Reasons to shop Medik8

Free UK delivery over £25
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A sleek white pump bottle of r-Retinoate Day & Night stands upright, with a swirl of white cream next to it.
r-Retinoate® Day & Night
  • Brighten
  • |
  • Smooth
  • |
  • Revive
 Youth Activating Cream
Full Size (50ml)
Key Benefits
Astonishing Age-Defying Results

Proven to simultaneously improve the look of skin brightness, uneven tone and dark spots - even on sensitive skin.

5-in-1 Time Saver

Combines 5 of Medik8’s most advanced age-defying technologies for the fastest, most effective, all round age-defying results in one masterpiece formula.

8x Stronger & 11x Faster Than Retinol

Combines Medik8-exclusive encapsulated retinyl retinoate (8x more powerful than retinol*) with our patented crystal-stabilised retinal (11x faster than retinol**), for previously unattainable age-defying results.

*H. Kim et al., Synthesis and in vitro biological activity of retinyl retinoate, a novel hybrid retinoid derivative, Bioorganic & Medicinal Chemistry, 2008, 15;16(12), pp 6387-93
**G. Siegenthaler et al., Retinol and retinal metabolism, Biochemical Journal, 1990, 268, pp 371-378

Simplifies Your Nighttime Regime

Delivers your nighttime serum and cream in one, removing the need for multiple steps in your evening routine.

Proven Results
AFTER
AFTER
7 days to visibly brighter, more even-toned skin*
4 weeks to dramatic visible wrinkle reduction*
4 weeks to visibly reduced dark spots*
96% agree the all-in-one cream made their routine simpler and shorter*
96% agree r-Retinoate Intense is non-irritating on the skin*
*Proven via independent consumer study on r-Retinoate Intense on 52 participants over 4 weeks.
How to Use

First-time use

If you're new to r-Retinoate Intense, we recommend a patch test at least 24 hours before first use. Learn how to patch test here.

Phase application in gradually. Use twice a week for the first 2 weeks, every other night for the next 2 weeks, then every night.

Step 1

After cleansing in the evening, massage 2 pumps of r-Retinoate Intense evenly across face, neck and décolletage.

Step 2
Use a sunscreen every morning while using vitamin A. We recommend Advanced Day Ultimate Protect.

Uses per bottle

90
Guide to Layering
Step 1: Cleanse
Medik8 Surface Radiance Cleanse tube displayed on a clean white background with a large, translucent gel texture smear. Text identifies it as a Resurfacing AHA/BHA Mangosteen Cleansing Gel in a 150mL size.
Morning
Evening
Surface Radiance Cleanse™
Select a Size
Step 2: Target
A sleek white pump bottle of r-Retinoate Day & Night stands upright, with a swirl of white cream next to it.
Morning
Evening
r-Retinoate® Day & Night
Full Size (50ml)
Step 3: Moisturise
Medik8 r-Retinoate Intense Youth Activating Cream bottle displayed on a white background with a swatch of the peach-toned cream texture visible behind it.
Evening
r-Retinoate® Intense
Full Size (50ML)
Step 4: Eye
A white pump bottle of r-Retinoate Day & Night Eye Serum, with a droplet of product next to it.
Morning
Evening
r-Retinoate® Day & Night Eye Serum
Full Size (15ml)
Key Ingredients
Encapsulated Retinyl Retinoate

Patented and exclusive to Medik8, this unique vitamin A molecule is the breakthrough result of 8 years of expert research. Retinyl retinoate is proven to be 8x more powerful than classic retinol* in delivering astonishing age-defying results.

*H. Kim et al., Synthesis and in vitro biological activity of retinyl retinoate, a novel hybrid retinoid derivative, Bioorganic & Medicinal Chemistry, 2008, 15;16(12), pp 6387-93

Encapsulated Retinal

This next-generation vitamin A works to target the look of fine lines, wrinkles, hyperpigmentation and uneven skin texture - 11x faster than classic retinol.* Its unique antibacterial properties also help to visibly decongest the skin.

*G. Siegenthaler et al., Retinol and retinal metabolism, Biochemical Journal, 1990, 268, pp 371-378

Drone-Targeted Peptide

A youth-boosting copper peptide, encapsulated in an innovative polymer shell. It dives through the layers of the skin to specifically support collagen-producing cells for more youthful-looking skin.

Ceramide Complex

A unique combination of ceramides (alongside phytosterol and fatty acids) which mimic the skin’s natural lipid barrier to intensely restore and nourish.

Drone-Targeted Peptide

A youth-boosting copper peptide, encapsulated in an innovative polymer shell. It dives through the layers of the skin to specifically support collagen-producing cells for more youthful-looking skin.

Ceramide Complex

A unique combination of ceramides (alongside phytosterol and fatty acids) which mimic the skin’s natural lipid barrier to intensely restore and nourish.

Hyaluronic Acid

With the ability to attract and retain more than 1,000 times its own weight in water, hyaluronic acid draws moisture into the upper layers of the skin; leaving the complexion hydrated and visibly supple.

Full List of Ingredients
r-Retinoate® Intense
Intense Youth Activating Cream

Aqua (Water), Caprylic/Capric Triglyceride, Glycerin, Butylene Glycol, Isododecane, Squalane, Cetearyl Alcohol, Dimethicone, Cetearyl Olivate, Sodium Acrylate/Sodium Acryloyldimethyl Taurate Copolymer, Polylactic Acid, Cyclodextrin, PPG-12/SMDI Copolymer, Sorbitan Olivate, Titanium Dioxide, Eclipta Prostrata Extract, Phenethyl Alcohol, Melia Azadirachta Leaf Extract, Phenoxyethanol, Cholesteryl Nonanoate, Sodium Hyaluronate, Tocopheryl Acetate, Rubus Chamaemorus (Cloudberry) Seed Oil, Canola Oil, Xanthan Gum, Pentylene Glycol, Retinal, Retinyl Retinoate, Citric Acid, Alumina, Isostearic Acid, Lecithin, Polyglyceryl-3 Polyricinoleate, Polyhydroxystearic Acid, Stearic Acid, Ceramide AP, Moringa Oleifera Seed Oil, Sodium Lauroyl Lactylate, Vanilla Planifolia (Vanilla) Fruit Extract, Ethylhexylglycerin, Linoleic Acid, Palmitic Acid, Ceramide NP, Daucus Carota Sativa (Carrot) Seed Oil, Disodium EDTA, Phytosterols, Lonicera Japonica (Honeysuckle) Flower Extract, 3-O-Ethyl Ascorbic Acid, Lonicera Caprifolium (Honeysuckle) Flower Extract, Sodium Polyaspartate, Phytosphingosine, Parfum*, Copper Palmitoyl Heptapeptide-14, Heptapeptide-15 Palmitate, Ceramide EOP, Cholesterol, C12-16 Alcohols, Caprylyl Glycol, Carbomer, Hydrogenated Lecithin, Glyceryl Caprylate, Lactic Acid/Glycolic Acid Copolymer, Polyvinyl Alcohol, Phenylpropanol, BHT, Limonene, Linalool, Citral. *natural extracts

*Although we try our best to ensure this list of ingredients is accurate there may be product upgrades from time to time, or slight variants between different regions based on local laws, meaning the only definitive ingredient list is that which is printed on the product packaging.
  • Clinically proven formula
  • No artifical fragrance
  • No synthetic colours
  • Paraben free
Expert Recommended

"The most powerful age-defying formula we have ever made."

DANIEL ISAACS
Chief Product Officer
A circular headshot portrait of a man with light brown hair and green eyes, smiling neutrally. He is wearing a white lab coat with 'Medik8' embroidered on the pocket and a black button-up shirt. The background is white.

"r-Retinoate Intense is amazing!"

KATHERINE PATERSON
Aesthetician

"The only vitamin A that has improved my skin without irritation."

CAROLINE BARNES
Makeup Artist

Complete Your Regime

Reviews

Frequently Asked Questions

Can I use r-Retinoate Intense if I'm pregnant or breastfeeding?
As a cosmetics company, we are unable to provide product advice in relation to medical conditions such as pregnancy or breastfeeding. We strongly recommend discussing the ingredients with your GP or midwife before use. We do, however, generally recommend avoiding vitamin A use while pregnant or breastfeeding, which is why we offer a plant-based vitamin A alternative - Bakuchiol Peptides.
How and when should I apply r-Retinoate Intense?
r-Retinoate Intense should be applied in the evening. After cleansing, massage 2 pumps evenly across the face, neck and décolletage.
r-Retinoate® Intense
Full Size (50ML)
Full Size (50ML)