A brown glass dropper bottle of Calmwise Serum stands upright on a white surface, surrounded by clear serum droplets.
A brown glass dropper bottle of Calmwise Serum is featured. Three bullet points with checkmarks list benefits: Visibly calms redness & helps to relieve sensitivity, Helps to improve skin barrier function against external irritants, and Leaves skin feeling nourished & comforted.
Close-up of an open amber glass bottle of Medik8 Calmwise Serum tipped on its side, pouring a pool of liquid onto a light surface. Text highlights key ingredients: Teprenone (helps strengthen the skin’s protective barrier against sensitivity) and Organic Sage Extract (helps soothe skin while protecting it against external irritants).
A HOW TO LAYER diagram for skincare routines. The AM routine includes Cleanse (Calmwise Soothing Cleanser), Target (Calmwise Serum), Vitamin C (C-Tetra), and Sunscreen (Advanced Day Ultimate Protect). The PM routine involves Cleanse (Calmwise Soothing Cleanser), Target (Calmwise Serum), Vitamin A (Crystal Retinal), and Moisturise (Advanced Night Restore).
A 15mL amber glass dropper bottle of Medik8 Calmwise Serum standing next to its white cardboard carton against a clean white background. Text on both the bottle and carton describes it as a "Soothing Elixir for Redness-Prone Skin."
A brown glass dropper bottle of Calmwise Serum stands upright on a white surface, surrounded by clear serum droplets.
A brown glass dropper bottle of Calmwise Serum is featured. Three bullet points with checkmarks list benefits: Visibly calms redness & helps to relieve sensitivity, Helps to improve skin barrier function against external irritants, and Leaves skin feeling nourished & comforted.
Close-up of an open amber glass bottle of Medik8 Calmwise Serum tipped on its side, pouring a pool of liquid onto a light surface. Text highlights key ingredients: Teprenone (helps strengthen the skin’s protective barrier against sensitivity) and Organic Sage Extract (helps soothe skin while protecting it against external irritants).
A HOW TO LAYER diagram for skincare routines. The AM routine includes Cleanse (Calmwise Soothing Cleanser), Target (Calmwise Serum), Vitamin C (C-Tetra), and Sunscreen (Advanced Day Ultimate Protect). The PM routine involves Cleanse (Calmwise Soothing Cleanser), Target (Calmwise Serum), Vitamin A (Crystal Retinal), and Moisturise (Advanced Night Restore).
A 15mL amber glass dropper bottle of Medik8 Calmwise Serum standing next to its white cardboard carton against a clean white background. Text on both the bottle and carton describes it as a "Soothing Elixir for Redness-Prone Skin."
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Calmwise™ Serum

  • Calm
  • |
  • Strengthen
  • |
  • Support
Soothing Elixir for Redness-Prone Skin

Visibly calm redness and relieve sensitive skin with Calmwise serum.

Formulated with teprenone (a patented anti-redness active), this lightweight serum helps to combat various kinds of redness by improving the skin's barrier function.

Redness caused by the likes of dryness, irritants and environmental stressors is visibly reduced while the complexion is left feeling nourished and comforted.

Please Note: Product packaging shown may be different to the product received due to regional variations
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An open frosted glass jar of Medik8 Total Moisture Daily Facial Cream with a peak of white cream on top, set against a clean white background. Badges in the top corners indicate it is a "Daisy Beauty Awards Vinnare 2025" (Winner) and "Dermatologist Recommended."
Total Moisture Daily Facial Cream™
  • Hydrate
  • |
  • Plump
  • |
  • Support
 AM/PM Multi-Layered Moisturisation with H.E.O.® & Prebiotic Peptides
Select a Size
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Sustainability

Provenance provides confidence for sustainability claims; helping to prevent 'green-washing' and empowering conscious consumers to purchase in line with their values. Provenance 'Proof Points' are all third party verified and evidenced through supply chains.

Product proof points

The Vegan Trademark

Certified to contain no animal products or byproducts and has not been tested on animals.

Partly Recyclable Packaging

Recyclable Parts: Bottle (glass) and Container (cardboard) Non-Recyclable Parts: Pipette

Partly Recycled Packaging

Recycled parts: bottle (40% recycled glass) Non-recycled parts: pipette and cardboard box

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B Corporation

Medik8 is a certified B Corporation, scoring over 80 out of 200 across Governance, Workers, Community, Environment and Customers. The certification includes a legal commitment to consider all stakeholders in decision-making. Verified every three years.

SBTi Approved Targets

Medik8 has SBTi approved science-based targets to reduce greenhouse gas emissions in line with limiting global warming to 1.5°C or well-below 2°C. Progress is reported publicly every year, with targets validated by the certifier and reviewed every 5 years.

Living Wage Employer

Medik8 is a Living Wage Employer — all staff are paid a wage calculated to meet the cost of living in the UK. Company wages are updated annually after new rates are announced by the Living Wage Foundation.

Donates to Charity

In 2022 Medik8 donated £10,000 to the National Society for the Prevention of Cruelty to Children

Carbon Measured

The footprint was calculated using GHG Protocol methodology; GWP 100.

Renewable Energy

Medik8's Innovation Centre uses electricity from 100% renewable sources.

Made in Britain

Medik8 carries the Made in Britain trademark — manufactured in the United Kingdom. Subject to facility verification and annual renewal.

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Key Benefits
Visible Redness Reduction

Calmwise Serum's key ingredient, teprenone, has been found to visibly reduce skin redness in 1 month.*

*Independent trial by Sederma

Comfortable, Visibly Restored Skin

The fragrance-free formula won't aggravate irritated skin further but, instead, leaves it feeling calm, comfortable and visibly restored.

Skin Barrier Support

Helps to strengthen the skin's barrier function against the redness-inducing effects of moisture loss and environmental stressors.

How to Use

Step 1

If you're new to Calmwise Serum, we recommend a patch test at least 24 hours before first use. Learn how to patch test here.

After cleansing in the morning and evening, massage 6 drops across the face where required.

Step 2

Leave to absorb before applying a moisturiser.

Step 3

Follow with a sunscreen in the morning.

Uses per bottle

75
Guide to Layering
Step 1: Cleanse
Medik8 Calmwise Soothing Cleanser pump bottle displayed on a white background with a smear of white foam behind it, highlighting the product's texture.
Morning
Evening
Calmwise™ Soothing Cleanser
Select a Size
Step 2: Target
A brown glass dropper bottle of Calmwise Serum stands upright on a white surface, surrounded by clear serum droplets.
Morning
Evening
Calmwise™ Serum
(0)
Step 3: Brighten
Medik8 C-Tetra Advanced bottle displayed on a clean white background with translucent serum droplets, highlighting its lightweight gel-serum texture.
Morning
C-Tetra® Advanced
Full Size (30ml)
Step 4: Renew
Crystal Retinal®
Evening
Crystal Retinal®
Select a Strength
Step 5: Moisturise
An open frosted glass jar of Medik8 Total Moisture Daily Facial Cream with a peak of white cream on top, set against a clean white background. Badges in the top corners indicate it is a
Morning
Evening
Total Moisture Daily Facial Cream™
Select a Size
Key Ingredients
Teprenone

A patented active that helps to soothe visible redness while supporting the skin barrier against external irritants.

Organic Sage Extract

A powerful, natural antioxidant that helps to protect skin against irritating external stressors. It also possesses anti-inflammatory properties to help calm both the look and feel of redness-prone skin.

Full List of Ingredients
Calmwise™ Serum
Soothing Elixir for Redness-Prone Skin

Simmondsia Chinensis (Jojoba) Seed Oil, Cyclopentasiloxane, Cyclohexasiloxane, Caprylic/Capric Triglyceride, Tocopheryl Acetate, Teprenone, Salvia Officinalis (Sage) Extract.

*Although we try our best to ensure this list of ingredients is accurate there may be product upgrades from time to time, or slight variants between different regions based on local laws, meaning the only definitive ingredient list is that which is printed on the product packaging.
Expert Recommended

Helps to strengthen the skin barrier to prevent any redness flare-ups.

CHARLOTTE BITMEAD
Senior Beauty Writer - Cosmopolitan

Reduced my redness to the point where I sometimes forget to apply it.

KIRSTEN L
Verified Medik8 Customer

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Frequently Asked Questions
Calmwise™ Serum