Skincare with Peptides

Peptides, naturally found in the skin, are essential building blocks of proteins that keep skin smooth, firm, and youthful. Applied topically, they stimulate collagen and boost elasticity, visibly reducing the appearance of fine lines and wrinkles. Our innovative peptide skincare products feature expertly engineered peptide combinations for brightening, clarifying, and hydrating effects - delivering maximum results.

12 Products

Advanced Pro-Collagen+ Peptide Cream

Rejuvenating Anti-Wrinkle Moisturiser With Growth Factor MiniProteinTM & NAD+ Longevity Booster

50ml / £79

Liquid Peptides Advanced MP

Wrinkle reduction serum with 30% multi-peptide complex - proven to deliver results in as little as 10 minutes.¹

30ml / £79

Liquid Peptides™

Hydrating multi-peptide serum - Targets the first signs of ageing and prevents fine line formation.

30ml / £59

Oxy-R Peptides™

High-Strength Oxyresveratrol Brightening Peptide Serum

2 x 10ml / £65

Clarity Peptides™

10% Niacinamide-Infused Peptide Serum

30ml / £45

Bakuchiol Peptides™

Retinol Alternative Peptide-Infused Serum

30ml / £55

Copper PCA Peptides™

Mineral Antioxidant Peptide Serum

30ml / £65

Eyelift™ Peptides

Age-Defying Firming Gel

15ml / £45

Total Moisture Daily Facial Cream™

AM/PM Multi-Layered Moisturisation with H.E.O.® & Prebiotic Peptides

50ml / £48

Total Moisture Daily Facial Cream Refill™

AM/PM Multi-Layered Moisturisation with H.E.O.® & Prebiotic Peptides

50ml / £43

Liquid Peptides™ (Travel Size)

30% Complex Multi-Peptide Serum

8ml / £20

Total Moisture Daily Facial Cream™ (Travel size)

AM/PM Multi-Layered Moisturisation with H.E.O.® & Prebiotic Peptides

12.5ml / £16

Liquid Peptides™ (Outlet)

30% Complex Multi-Peptide Age-Defying Serum

30ml / 8ml / £24

Frequently Asked Questions

How often and when should you apply peptides in your skincare routine?

Peptides are gentle enough for daily use and can be applied both morning and evening after cleansing. Use a peptide serum before your moisturiser, or opt for a peptide-rich cream if you prefer a simplified routine.

Medik8’s Liquid Peptides Advanced MP is a lightweight, fast-absorbing serum that delivers targeted, clinical-grade peptide technology to visibly smooth expression lines and improve skin firmness, suitable for all skin types. If you're looking to visibly brighten the complexion and reduce the appearance of dark spots or post-blemish marks, Oxy-R Peptides is a targeted formula suitable for all skin tones.

What are the benefits of peptides for the skin?

Peptides support collagen and elastin production to help improve firmness and elasticity. With consistent use, peptides can help reduce the appearance of fine lines, smooth texture, and boost overall skin resilience. They also work to strengthen the skin barrier, enhancing hydration and reinforcing the skin’s natural defences for a plumper, more radiant complexion.

What do peptides do for the under-eyes?

Peptides help to support the delicate skin under the eyes by encouraging collagen production and strengthening the skin barrier. This can reduce the appearance of fine lines, improve firmness and minimise puffiness over time. The gentle nature of peptides makes them ideal for this sensitive area, helping to restore a smoother, more refreshed look.

Which peptides are best for anti-ageing?

Different peptides target different signs of ageing, which is why combining them often delivers the most visible results. Signal peptides help stimulate collagen production, while neurotransmitter peptides visibly smooth expression lines. Carrier peptides support skin regeneration, and enzyme-inhibitor peptides help slow the breakdown of collagen and elastin.

Medik8’s Liquid Peptides Advanced features a 30% blend of 10 carefully selected peptides, including our pioneering Dual MiniProteins™. This next-generation formula is clinically proven to visibly reduce both expression lines and deeper wrinkles, offering comprehensive, targeted support for firmer, smoother-looking skin[1].

[1]To verify visit: https://www.medik8.com/pages/circana-group-claim-letters-liquid-peptides-advanced-mp

When should you apply peptides in your skincare routine?

Peptides can be applied in both the morning and evening after cleansing. Apply a peptide serum before your moisturiser, or choose a peptide-rich cream that can be used on its own. Medik8’s Liquid Peptides Advanced is a lightweight, fast-absorbing formula suitable for all skin types. For those looking to target uneven skin tone, Oxy-R Peptides helps to visibly brighten the complexion and reduce dark spots and post-blemish marks.

At what age should you start using peptide skincare products?

Peptides can benefit skin at any age, but they're particularly valuable from your mid-twenties onwards when natural collagen production begins to decline. Starting peptide treatments early helps maintain skin firmness and prevent premature signs of ageing. However, peptides are equally effective for mature skin, helping to restore elasticity and smooth existing lines and wrinkles through enhanced collagen synthesis.

Can you use peptides when pregnant?

Peptides are generally considered safe to use during pregnancy. Unlike ingredients such as retinoids, peptides do not pose known risks and can continue to support the skin through hydration and repair. However, if you’re unsure, it’s always best to check with a healthcare provider.

Can you use peptides with retinol?

Peptides and retinol aren’t rivals, they’re complementary. While retinol encourages skin renewal and boosts collagen production, it can sometimes cause dryness or irritation, particularly for sensitive skin. Peptides, on the other hand, help to firm, smooth and support the skin barrier more gently.

Using both in a balanced routine can deliver powerful results. Peptides can help buffer the effects of retinol, making the combination ideal for visibly improving signs of ageing without compromising comfort. 

Medik8’s Crystal Retinal pairs well with Liquid Peptides in a balanced evening routine.

Can you use peptides with vitamin C?

Peptides can be used with vitamin C without any issues. Vitamin C brightens and protects the skin, while peptides work to improve skin firmness and smoothness. Together, they offer a complementary approach to ageing concerns, helping to promote a radiant and resilient complexion. Apply vitamin C in the morning, followed by a peptide serum or moisturiser such as Daily Radiance Vitamin C or Clarity Peptides.

What is the best age to start peptide serum?

Peptides can be introduced into your skincare routine from your mid-20s onwards, when collagen production naturally begins to decline. They’re a great way to support the skin early on, helping to maintain firmness and prevent the early signs of ageing, without the need for stronger active ingredients.

What not to mix peptides with?

Peptides are generally well-tolerated and pair well with most skincare ingredients. However, it's best to avoid using them alongside high concentrations of low pH acids, such as strong AHAs or vitamin C, as this may reduce their effectiveness. If you're using both, alternate them between your morning and evening routines to get the full benefit.

Are peptides suitable for sensitive skin?

Yes, peptides are generally very well tolerated, even by sensitive skin. Their gentle nature makes them ideal for supporting skin that’s prone to irritation, as they help to calm, hydrate and reinforce the skin barrier. As with any new product, we recommend patch testing first, especially if your skin is reactive or compromised.

Which types of peptides are most effective?

Peptides are a diverse group of active ingredients, each designed to target specific skin concerns. 

  • Signal peptides help stimulate collagen production, 
  • Carrier peptides support skin repair
  • Neurotransmitter peptides work to visibly soften the appearance of expression lines.

The most advanced formulations combine multiple peptide types to deliver comprehensive anti-ageing benefits and support overall skin renewal.

Liquid Peptides Advanced is Medik8’s next-generation peptide serum, formulated with a 30% multi-peptide blend and powered by Dual MiniProteins™ to visibly target both early and deep-set wrinkles.