(30ml)

How to Buy


 

PRETOX® Filler
Professional Strength
Injection-Free alternative to Dermal Filler treatment to plump cheeks & neck


Clear crystalline formula with hyaluronic acid to lift wrinkles, nasal-labial folds, brows’ furrows and sagging skin. Incorporating a smart liposome delivery system to transport 30% hyaluronic acid into the deep skin layers requiring treatment without the need for painful injections. Helps to regain the skin’s natural hydro balance, correct skin irregularities and plump out cheeks.

Wrinkles and lines are literally folds in the skin where there is a lack of 'supporting scaffolding' underneath the surface. Pretox Filler® plugs the 'holes' under the folds with Hyaluronic Acid, a naturally occurring bio-molecule found within the skin, where it contributes to cell proliferation, helping to build the “scaffolding” structure of the dermis.

Pretox Filler® is injection-free and uses a smart liposome delivery system to accurately target actives to the deep layers requiring treatment. Pretox Filler® contains several advanced and clinically proven actives, including Palimitoyl Tetrapeptide, which has been shown in studies to stimulate the development of new collagen, elastin and glycosaminoglycans in the skin, and is also anti-inflammatory. It restores the cytokine balance of mature skin, which is responsible for many of the signs of ageing. Pretox Filler® also contains Superoxide Dismutase, Medik8’s very own Moisture Magnet™ to prevent excessive water loss, and importantly over 30% of Hyaluronic acid (pH6.5) – the skin's natural scaffolding pre-cursor.

Pretox Filler protects the extra cellular matrix of the skin, increases skin firmness, elasticity and hydration.


Pretox Range

Injection Free is a specialist treatment cosmeceutical range based on the critical discoveries in the global beauty industry and Medik8’s own research. The gel formula reduces the appearance of all types of wrinkles: dynamic, static and wrinkle folds.

Dynamic wrinkles are formed as a result of facial muscles contractions. Thus the most common locations of dynamic wrinkles are on the forehead, on the outer corners of the eyes (the so called “crow’s feet”) and between the eyebrows. When muscles contract, they cause the overlaying skin to crumple and form lines. Probably the most effective and popular treatment against dynamic wrinkles is Botulinum Toxin A. The treatment works by paralysing the muscles of facial expression, thus preventing their contraction and new lines from forming. Pretox Infin8  is a second-generation injection-free solution to anyone over their 40s onwards, who would like to obtain similar results to Botulinum Toxin A treatment, without drastic measures. Pretox Infin8 effectively rejuvenates the skin by working on all three layers of skin and on the muscular filaments, responsible for the facial expression.




 
Hyaluronic acid (also known as Hyaluronan or Sodium Hyaluronate) is non-sulphated glycosaminoglycan widely present in human tissue, especially in the skin. Along with collagen and elastin fibres, it is one of the principal elements of the extra cellular matrix and acts as a mediator in cell proliferation and migration.

Hyaluronic acid stands out above nearly all other bio available and synthetic polymers in hydrophilic properties’ rank. Not only does it show eminent ability to bond with water (H2O) through hydrogen bonding (one molecule of hyaluronic acid can bind up to 250 water molecules) but it also exhibits extraordinary biological compatibility.

When applied to the skin, hyaluronic acid creates a clear, translucent and invisible film on the epidermis, which helps to retain moisture on the skin as well as restore and maintain its silky, flexible and resilient properties. The improvement of the barrier function of the skin is central to the improvement of dry, ageing skin as the tissue hydration is preserved.

Dermal Filling Treatments with Hyaluronic acid are extremely effective and are absolutely safe since Hyaluronic acid molecules are enzyme-degraded. After approximately 6-12 months from the injection, Hyaluronic acid molecules are subject to degradation into carbon dioxide and water, which are entirely absorbed by the body. Although the advantage is that the treatment is 100% safe, the injections have to be repeated regularly to sustain results. Pretox Filler, on the other hand, attempts to plug the gaps in the extracelluar matrix with Hyaluronic Acid using Liposome technology without the need for painful injections and with longer lasting effects. Continuous use of Pretox Filler maintains the levels of HA at a high level, protecting the skin from dryness and wrinkle formation.

The study of Skin Smoothness after treatment with Pretox Filler has shown an improvement in skin regularity by 23.3%, increase in hydration by 24% and reduction in skin roughness by 14.2%. Skin firmness has been shown to go up by 40% and the elasticity increase was marked by 27%.

Since it is the first glycosaminoglycan to be synthesised immediately after injury, it has also been suggested that hyaluronan may be therapeutically useful not only in anti-ageing skincare regimes but also in would repair.


 

Apply twice daily to targeted areas, ensuring skin is clean & dry. Pretox Filler® should be used over cheeks, nasal labial lines (smile lines) and jaw line. Avoid upper & lower eyelids and lips. Allow to absorb for 3-5 minutes before applying solution-based products, hydrator, sunscreen and/or make up.

To view the application areas and protocol click below:


View the Medik8 Skin Zones


Highly compatible for use with Medik8 Titanium Dermaroller 0.2mm and 0.3mm
Aqua (Water), Saccharide Isomerate, Alcohol Denat. (Ethanol B100), Palmitoyl, Glycerin, Xanthan Gum, Superoxide Dismutase, Phenoxyethanol, Sodium Hyaluronate, Ethylhexylglycerine

Patents Pending.




Key active highlights:

For full details on the key actives and bases, please see the Medik8 ingredient sheets or contact us for more information.

Hyaluronic Acid (pH 6.5) - Smoothes wrinkles by adding volume under the skin – “scaffold plumping”

Moisture Magnet™
- Proprietary trademarked blend of humectants

Copper Superoxide Dismutase complex
- Powerful antioxidant

 



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Go Back to Pretox Range

Medik8 is the British skin research company pioneering cosmeceutical technologies to make the most effective ingredients suitable for even the most sensitive skin, yet crucially without compromising efficacy. Medik8 cosmeceuticals may be used by everyone. Apart from being kinder to the skin, it turns out this new technology is kinder to the planet too. That’s why Medik8 is known as the ‘Green Cosmeceutical’ brand. Most skin is sensitive, it is just to what degree that distinguishes it from others. A simple change of washing powder can demonstrate this. People of all ages and skin types can periodically suffer from sensitive skin, making them particularly susceptible to certain irritating cosmeceutical ingredients. In fact, those suffering from acne, rosacea or psoriasis usually have greater skin sensitivity, which can be exacerbated by some aggressive treatment products that they use. The challenge for Medik8 is to make effective ingredients less aggressive without reducing potency. We do this in many ways for example using film-encapsulation, chirally correct actives, non-acid derivatives and patented anti-erythema technologies. Of course, using any effective strength actives, for example retinols and fruit acids, will cause some stinging to even the toughest skins, but Medik8 pharmacologists have minimised the degree of irritation and in some cases made it absent all together. No longer are the most powerful and effective ingredients beyond the reach of people who want the gain without the pain! And who doesn’t want that? Ask your skin care professional about what Medik8 can do for you.

The information on the website is not intended for a U.S. Audience. These statement have not been evaluated by the Food and Drug Administration.
These products are not intended to diagnose, treat, cure, or prevent any disease.